Volume-5, Issue-6, June 2019

Abstract

Safety of drug is very important. Pharmacovigilance Programme is there in India to reports any adverse reaction of drugs (ADRs). So this study was conducted to assess the knowledge of interns regarding pharmacovigilance. This cross sectional study was conducted at medical colleges of Rajasthan during the period of Oct. 2017 to April 2018. For this study, 150 medical students of internship were enrolled. Clearance from institutional ethical committee was taken prior to the study and written informed consent was taken from all the study participants. Knowledge of these intern students was assessed by a predesigned semi structured questionnaire. In the present study, 64% medical students gave correct response regarding the definition of pharmacovigilance. 65% students were aware that the most important purpose of pharmacovigilance is to identify safety of the drug. Only 42% of students were aware regarding the existence of a Pharmacovigilance Programme in India. 60% of interns were aware that the regulatory body responsible for monitoring ADRs in India is Central Drugs Standard Control Organization (CDSCO). 74% interns gave correct answer regarding professionals is responsible for reporting ADRs in a hospital. 95% agreed that ADR reporting is a professional responsibility for them. So it can be concluded that there is a great need to generate awareness regarding Pharmacovigilance among medical professionals and also to promote the reporting of ADRs. Reporting of ADRs is compulsory and it should be made an integral part of the patient care.

Keywords: Adverse drug reactions, Knowledge, Pharmacovigilance.

References

Keywords: Adverse drug reactions, Knowledge, Pharmacovigilance.

Abstract

Congenital heart diseases (CHD) are the anatomical abnormalities present at the birth resulting in abnormal cardiac function. Children with congenital heart diseases may grow or develop more slowly than other children. The present study was conducted with the objectives to assess the physical growth and development of children with CHD. A descriptive study was undertaken on 103 children with CHD attending/admitted in selected units of Advanced Cardiac Centre and Advanced Pediatric Centre PGIMER Chandigarh by Interview of parents and observation of children. Questionnaire contained four parts socio-demographic profile of Parents, Clinical profile of children, WHO growth charts and Vineland Social Maturity Scale. This study observed that most of children were toddlers (62.5%) and male child (62.5%).Most of children(91.3%) were diagnosed less than three years of age and most of children(41.3%) found suffering from ventricular septal defect (VSD). According to WHO 'z' scoring 31.7% of children were found severely stunted, 53.8% were found severely underweight. And 37.5% children were severely wasted and 55.8% children had below average intelligence. The present study concluded that some of children had growth retardation (i.e. severely stunted, severely underweight and severely wasted) and developmental delay (below average intelligence). It was also seen that there was no association of socio-demographic characteristics with their growth pattern.

Keywords: Congenital heart diseases (CHD), Physical Growth, Development.

References

Keywords: Congenital heart diseases (CHD), Physical Growth, Development.